Figure 1.

The administration of dental pulp stem cell‐conditioned media (DPSC‐CM) improved the delay in sciatic nerve conduction velocities, and the decrease in sciatic nerve blood flow and intraepidermal nerve fiber density in diabetic rats. (a) Sciatic nerve motor nerve conduction velocities. Motor nerve conduction velocity was measured between the ankle and sciatic notch (n = 5–7). (b) Sciatic nerve sensory nerve conduction velocities. Sensory nerve conduction velocity was measured between the ankle and knee (n = 5–7). (c) Sciatic nerve blood flow. Sciatic nerve blood flow was measured using a laser Doppler blood flow meter (n = 5–7). (d) Intraepidermal nerve fiber density of the footpads (n = 4). The results are presented as the mean ± standard error of the mean. **P < 0.01. Measurements were carried out 4 weeks after the DPSC‐CM injection.