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. 2019 Aug;189(8):1513–1525. doi: 10.1016/j.ajpath.2019.04.013

Figure 8.

Figure 8

Proposed schematic diagram: cadmium (Cd)–potentiated inflammation by respiratory syncytial virus (RSV) infection. Low-dose Cd–potentiated RSV infection caused lung inflammation and injury by dysregulating metals, disrupting mitochondrial metabolism, stimulating oxidative stress, and elevating proinflammatory cytokines, chemokines, and infiltration of immune cells. KC, keratinocyte cytokine; RANTES, regulated on activation, normal T cells expressed and secreted; TrxR2, thioredoxin reductase 2.