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. 2019 Sep 2;20:184. doi: 10.1186/s13059-019-1785-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Trends in drug resistance amongst K. pneumoniae and Enterobacter spp. isolated from patients attending CUH between 2000 and 2012. The proportion of a Klebsiella pneumoniae and b Enterobacter spp. resistant to one group of antimicrobials or less (pale shading), two groups (mid-shading), or three or more groups (dark shading) are shown, and a major change in national antimicrobial prescribing practice in 2007 is denoted with a red vertical line. Black vertical lines represent 95% confidence intervals. Resistance to cephalosporins and/or aminoglycosides in K. pneumoniae or aminoglycosides in E. cloacae is shown for isolates from Cambridge alone (dashed white line) and the UK (dotted white lines) (UK data from www.bsacsurv.org)