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Mean (%CV) SBECD Pharmacokinetic Parameters Following IV Administration of Delafloxacin 300 mg (Containing 2400 mg SBECD) to ESRD Patients
| Plasma Pharmacokinetics | Dosing Before Hemodialysis | Dosing After Hemodialysis |
|---|---|---|
| Cmax (μg·hr/mL) | 238 (24.6) | 304 (28.3) |
| AUC0‐48 | 2715 (58.3) | 7861 (31.6) |
AUC indicates area under the concentration‐time curve; Cmax, peak concentration; %CV, coefficient of variation; ESRD, end‐stage renal disease; IV, intravenous; SBECD, sulfobutylether‐β‐cyclodextrin.
