Table S2.
Age-standardized sex-specific prevalence of LADA and type 1 diabetes after removal of low GADA titer LADA patients
| Age, years | Male | Female | LADA after removal of low GADA titer patients | Total T1DM (defined as Classic T1DM and LADA after removal of low GADA titer patients | ||
|---|---|---|---|---|---|---|
| Male | Female | Male | Female | |||
| n | n | n (%) | n (%) | n (%) | n (%) | |
| 30–34 | 885 | 298 | 30 (3.39) | 14 (4.7) | 86 (9.72) | 42 (14.09) |
| 35–39 | 1106 | 394 | 30 (2.71) | 19 (4.82) | 69 (6.24) | 42 (10.66) |
| 40–44 | 1429 | 576 | 52 (3.64) | 14 (2.43) | 75 (5.25) | 32 (5.56) |
| 45–49 | 1607 | 955 | 40 (2.49) | 30 (3.14) | 72 (4.48) | 45 (4.71) |
| 50–54 | 1705 | 1442 | 37 (2.17) | 36 (2.5) | 64 (3.75) | 58 (4.02) |
| 55–59 | 1227 | 1076 | 21 (1.71) | 27 (2.51) | 41 (3.34) | 41 (3.81) |
| 60–64 | 1052 | 1055 | 23 (2.19) | 19 (1.8) | 29 (2.76) | 30 (2.84) |
| 65–69 | 675 | 657 | 8 (1.19) | 12 (1.83) | 17 (2.52) | 16 (2.44) |
| ≥70 | 656 | 554 | 12 (1.83) | 20 (3.61) | 15 (2.29) | 26 (4.69) |
| Crude rate | 10,342 | 7007 | 253 (2.45) | 191 (2.73) | 468 (4.53) | 332 (4.74) |
| Standardized† | 2.29 (1.75-2.83) | 2.82 (2.22–3.42) | 4.02 (3.32–4.72) | 4.77 (4.00–5.54) | ||
Notes: Data are expressed as n (%). Standardized prevalence was expressed as p (95% CI). By analyzing the GADA titer distribution in all age groups, we defined the Low GADA titer as lower than 80 U/mL and removed this part of LADA for possible false-positive rate.
Abbreviations: LADA, latent autoimmune diabetes of adults; GADA, glutamic acid decarboxylase autoantibody; T1DM, type 1 diabetes mellitus.