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COPD patients with frequent exacerbations (FEs) had higher levels of CRP and lower levels of SDC-1 (A-B). Serum SDC-1 correlated negatively with CRP in COPD patients (C). Diagnostic accuracy of serum SDC-1 to differentiate FE was calculated (D).
Abbreviations: CRP, C-reactive protein; COPD, chronic obstructive pulmonary disease; SDC, syndecan.
