Table I.
Associations between SMC1 expression in cancer tissue and clinicopathological characteristics in patients with colorectal cancer.
| SMC1 expression [N (%)] | |||||
|---|---|---|---|---|---|
| Clinicopathological characteristic | N | Low expression | High expression | χ2 | P-value |
| Total number | 51 | 22 | 29 | ||
| Sex | 0.448 | 0.503 | |||
| Male | 35 | 14 (63.64) | 21 (72.41) | ||
| Female | 16 | 8 (36.36) | 8 (27.59) | ||
| Age (years) | 0.015 | 0.903 | |||
| <65 | 25 | 11 (50.00) | 14 (48.28) | ||
| ≥65 | 26 | 11 (50.00) | 15 (51.72) | ||
| Location | 0.019 | 0.889 | |||
| Rectal cancer | 18 | 8 (36.36) | 10 (34.48) | ||
| Colon cancer | 33 | 14 (63.64) | 19 (65.52) | ||
| Cell differentiation | 3.960 | 0.138 | |||
| Well | 5 | 2 (9.09) | 3 (10.34) | ||
| Moderate | 20 | 12 (54.55) | 8 (27.59) | ||
| Poor | 26 | 8 (36.36) | 18 (62.07) | ||
| TNM | 7.322 | 0.007b | |||
| I/II | 26 | 16 (72.73) | 10 (34.48) | ||
| III/IV | 25 | 6 (27.27) | 19 (65.52) | ||
| Primary tumor size | 4.469 | 0.035a | |||
| T1-2 | 23 | 14 (63.64) | 9 (31.03) | ||
| T3-4 | 28 | 8 (36.36) | 20 (68.97) | ||
| Lymph node metastasis | 5.685 | 0.017a | |||
| N0 | 25 | 15 (68.18) | 10 (34.48) | ||
| N1-2 | 26 | 7 (31.82) | 19 (65.52) | ||
| Vascular invasion | 0.292 | 0.589 | |||
| No | 30 | 12 (54.55) | 18 (62.07) | ||
| Yes | 21 | 10 (45.45) | 11 (37.93) | ||
a
P<0.05
b
P<0.01. SMC1, structural maintenance of chromosomes 1.