Table 2.

Univariate and multivariate analyses of prognostic factors in validation cohort

Datasets	Variables	Single-variate factor analysis		Multi-variate factor analysis
HR (95% CI)	P-value	HR (95% CI)	P-value
TCGA	Age (65> vs ≤65)	1.36 (1.05–1.75)	0.02	1.38 (1.05–1.81)	0.02
	Stage (III, iV vs I, II)	2.44 (1.15–5.17)	0.02	2.30 (0.92–5.70)	0.07
	Debulking (suboptimal vs optimal)	1.26 (0.95–1.66)	0.10	1.15 (0.87–1.53)	0.33
	Grade (3, 4 vs 1, 2)	1.32 (0.92–1.90)	0.13	1.42 (0.95–2.10)	0.08
IRGPI (high vs low)	2.707 (2.05–3.57)	1.72E-12	2.56 (1.91–3.42)	2.20E-10

Abbreviations: HR, hazard ratio; CI, confident interval; IRGPI, immune-related gene pairs index.