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. 2005 Jan 24;2005(1):CD004096. doi: 10.1002/14651858.CD004096.pub2
Study Weight Glycemic control Lipids Blood pressure
Williams 1968 
 Study design: RCT 
 Follow‐up interval: 8 weeks 1. Weight change (kg) 
 Delta I (SE): ‐5.0 (0.4) 
 Delta C (SE): ‐3.7 (0.6) 
 Delta (I‐C) (SE): ‐1.3 (0.7)      
Silverstone 1966 
 Study design: RCT 
 Follow‐up interval: 26 weeks 1. Weight change (kg) 
 Delta I (SE): ‐5.0 (0.6) 
 Delta C (SE): ‐3.5 (1.9) 
 Delta (I‐C) (SE): ‐1.5 (2.0) 
 2. % of weight loss 
 Delta I (SE): ‐5.9 (0.8) 
 Delta C (SE): ‐3.9 (2.1) 
 Delta (I‐C) (SE): ‐2.0 (2.3)      
Bratusch‐Marrain 1979 
 Study design: RCT 
 Follow‐up interval: 8 weeks 1. Weight change (kg) 
 Delta I (SE): ‐3.9 (0.4) 
 Delta C (SE): ‐3.0 (0.5) 
 Delta (I‐C) (SE): ‐0.9 (0.6) 
 2. % of weight loss 
 Delta I (SE): ‐4.9 (0.5) 
 Delta C (SE): ‐3.3 (0.5) 
 Delta (I‐C) (SE): ‐1.6 (0.7)      
Hendon 1962 
 Study design: Pre vs post 
 Follow‐up interval: 40 weeks 1. Weight change (kg) 
 Delta I (SE): ‐8.8 (1.0)      
Mentenero 1964 
 Study design: Pre vs post 
 Follow‐up interval: 20‐240 days 1. Weight change (kg) 
 Group 1 
 Delta I (SE): ‐5.3 (0.6) 
 Group 2 
 Delta I (SE): ‐4.6 (0.9) 
 2. % of weight loss 
 Group 1 
 Delta I (SE): ‐5.2 (2.1) 
 Group 2 
 Delta I (SE): ‐3.9 (3.2)