Outcome	Follow‐up 8‐16w				Follow‐up 24‐26w
	No. of studies	N	Point estimate	95% CI	No. of studies	N	Point estimate	95% CI
Weight (kg)	5	192	‐3.4	(‐5.2, ‐1.7)	4	97	‐5.1	(‐6.90, ‐3.26)
percent weight loss					1	20	‐2.5	(‐7.9, 3.0)
% participants with weight loss >5%
BMI (kg/m2)	1	47	‐0.5	(‐1.0, ‐0.1)
Waist circumference (cm)
GHb (%)	4	145	‐1.0	(‐1.5, ‐0.4)	4	97	‐1.0	(‐1.4, ‐0.6)
Fasting glucose (mmol/l)	5	192	‐0.9	(‐2.1, 0.4)	4	97	‐0.9	(‐2.0, 0.2)
SBP (mm Hg)
DBP (mm Hg)
Total cholesterol (mmol/l)	2	85	‐0.1	(‐0.3, 0.2)	1	17	0.1	(‐0.4, 0.6)
LDL cholesterol (mmol/l)
HDL cholesterol (mmol/l)	1	68	0	(‐0.1, 0.1)
Triglycerides (mmol/l)	2	85	‐0.5	(‐1.1, 0.1)	1	17	‐0.2	(‐1.0, 0.7)