Study	Drug dosage	Int. attrition(%)	Control attrition(%)
Fluoxetine Connolly 1995 Daubresse 1996 Gray 1992 Kutnowski 1992 O'Kane 1994 Zelissen 1992	60 mg qd 60 mg qd 60 mg qd 60 mg qd 60 mg qd 60 mg qd	27.0 20.5 33.0 14.9 22.0 0.0	15 13.9 17.0 10.0 10.0 0.0
		20.1 (0‐33.0) mean(range)	12.1 (0‐17.0) mean(range)
Orlistat Bloch 2003 Hollander 1998 Kelley 2002 Kelley 2004 Hanefeld 2002 Lindgarde 2000 Miles 2002 Wang 2003	120 mg tid 120 mg tid 120 mg tid 120 mg tid 120 mg tid 120 mg tid 120 mg tid 120 mg bid‐tid	6.7 14.7 49.0 34,6 33.0 NR 35.0 3.2	22.4 27.7 52.0 15.4 29.2 NR 44.0 0
		25.2 (3.2‐49.0)	27.2 (0‐52.0)
Sibutramine Finer 2000 Fujioka 2000 Gokcel 2001 Kaukua 2004 McNulty 2003 Redmon 2003 Serrano‐Rios 2002 Tankova 2003	15 mg qd 5‐10 mg qd 10 mg bid 15 mg qd 15 or 20 mg qd 10‐15 mg qd 15 mg qd 10‐15 mg qd	9.0 33.0 3.0 8.0 24.6 10.0 23.2 NR	9.0 29.0 17.0 11.0 28.1 6.9 12.0 NR
bid, twice daily Int, intervention NR, not reported qd, daily		15.8 (3.0‐33.0) mean(range)	16.0 (6.9‐29.0) mean(range)