| Methods |
Study design: RCTRandomization procedure: NRAllocation concealment: UnclearFollow‐up: 26w |
| Participants |
Country: ScotlandSetting: Diabetic clinicNumber: 30Age: 66Sex: 38%FMedications: Diet onlyBL wt: I 92.0, C 85.1BL BMI: I 32.0, C 31.5BL GHb: I 8.0, C 8.7 |
| Interventions |
Drug: FluoxetineDosage: 60mg qdDuration: 26wDiet: 1200‐1600 kcal/d, 50% CHOComparison: Placebo + diet |
| Outcomes |
Weight: YesBMI: Yes>5% loss (%):FBS: YesGHb: YesCholesterol:LDL:HDL:TG:SBP:DBP:Side effects: Yes |
| Notes |
Funding: Lilly Industries, Ltd.Abstract/full text: FTLOCF: NRITT: Yes, with attritionAttrition: 20%Blinding: Double‐blindBlinding assessor: UnclearBL comparable: UnclearJadad score: 1,1,0,BRisk of bias: C |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
