11. Karnofsky performance status.
| Study | Score 71% to 100% | Score 41% to 70% | Score 0% to 40% | P value1 | |||
| MSD‐HSCT | IST | MSD‐HSCT | IST | MSD‐HSCT | IST | ||
| % (N affected of N evaluable) | |||||||
| Bayever 1984 | 92 (24 of 26) | 46 (6 of 13) | 4 (1 of 26) | 54 (7 of 13) | 4 (1 of 26) | 0 (0 of 13) | < 0.001 |
| Führer 1998 | NR | NR | NR | NR | NR | NR | NR |
| Gratwohl 1981 | NR | NR | NR | NR | NR | NR | NR |
1We calculated the P value using Fisher's exact test.
Karnofsky performance status scale definitions according to NPCRC 2012: 71% to 100%: able to carry on normal activity and to work; no special care needed (100%: normal, no complaints); 41% to 70%: unable to work; able to live at home and care for most personal needs; varying amount of assistance needed; 0% to 40%: unable to care for self; requires equivalent of institutional or hospital care; disease may be progressing rapidly (0%: dead).
Abbreviations: IST: immunosuppressive therapy including ciclosporin and/or antithymocyte or antilymphocyte globulin; MSD‐HSCT: first‐line allogeneic hematopoietic stem cell transplantation from HLA‐matched sibling donor; N: number; NR: not reported