Comparison 1. Overall effect of taxanes.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall survival ‐ all studies	27	39180	Hazard Ratio (95% CI)	0.87 [0.83, 0.92]
1.1 All studies	27	39180	Hazard Ratio (95% CI)	0.87 [0.83, 0.92]
2 Disease‐free survival: all studies	30	41909	Hazard Ratio (95% CI)	0.88 [0.85, 0.92]
2.1 All studies	30	41909	Hazard Ratio (95% CI)	0.88 [0.85, 0.92]
3 Disease‐free survival: as defined in Cochrane protocol	25	35063	Hazard Ratio (95% CI)	0.86 [0.82, 0.89]
3.1 DFS ‐ excluding Boccardo, CALGB40101, NCIC‐CTG MA21 & RAPP‐01	25	35063	Hazard Ratio (95% CI)	0.86 [0.82, 0.89]