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. 2008 Jan 23;2008(1):CD006052. doi: 10.1002/14651858.CD006052.pub2
Methods Randomised double‐blind trial testing combination of resistance training and creatine. Method of randomisation was given on request.
Participants CMT1 and CMT2 patients based on clinical, electrophysiological and genetic diagnosis, 10 patients allocated to each group.
Interventions One group performing resistance training daily in combination with additional oral intake of 5mg creatine per day, one group receiving resistance training in combination with placebo 12 weeks.
Outcomes Muscle fibre typing and size, quantitative muscle assessment.
Notes 3 participants reported to have decreased their training due to delayed onset soreness.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate