Bradley 1988

Methods	Randomised double‐blind trial. Method of randomisation not given.
Participants	Two groups with 15 CMT participants each. CMT 1 and CMT2 included diagnosed clinically and electrophysiologically, no genetic testing.
Interventions	Initially 2 months placebo in both arms followed by 40mg. Cronassial versus placebo for 5 months followed by Cronassial 40mg versus 100mg for another 5 months, no wash out phase in between, mode of administration i.m. 12 weeks.
Outcomes	Sensory measures, strength measures, EMG, Nerve conduction velocities and sensory and motor action potentials.
Notes	1 drop out because of allergic rash under 100 mg Cronnassial, 1 drop out because of pain at injection site under 40 mg after 8 months.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear