Kato 2008.
Methods | Randomised clinical trial. | |
Participants | Country: Japan.
Number randomised: 85.
Post‐randomisation drop‐outs: 0.
Mean age: 66 years.
Females: not stated.
Major liver resections: not stated.
Cirrhotic livers: not stated. Inclusion criteria: Liver resection. |
|
Interventions | Participants were randomly assigned to two groups. Group 1: low CVP (n = 20). Group 2: control (n = 20). Further details of intervention: CVP was lowered by clamping the infra‐hepatic inferior vena cava. Other details: Vascular occlusion: intermittent PTC. Method of parenchymal transection: CUSA. Management of raw surface: diathermy, sutures, fibrin glue. Other co‐interventions to decrease blood loss: none reported. |
|
Outcomes | The outcomes reported were mortality, transfusion requirements, and hospital stay. | |
Notes | Attempts to contact the authors in November 2008 were unsuccessful. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "Eighty‐five patients who underwent hepatic resection....randomly assigned to an IVC clamping or an IVC non‐clamping group by the minimization method with stratified factors of age, .." |
Allocation concealment (selection bias) | Low risk | Quote: "Eighty‐five patients who underwent hepatic resection....randomly assigned to an IVC clamping or an IVC non‐clamping group by the minimization method with stratified factors of age, .." |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: This information was not available. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: This information was not available. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: There were no post‐randomisation drop‐outs. |
Selective reporting (reporting bias) | High risk | Comment: Important outcomes such as liver failure were not reported. |
Free of vested interest bias? | Unclear risk | Unclear. |