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. 2012 May 16;2012(5):CD007338. doi: 10.1002/14651858.CD007338.pub3

Kato 2008.

Methods Randomised clinical trial.
Participants Country: Japan. 
 Number randomised: 85. 
 Post‐randomisation drop‐outs: 0. 
 Mean age: 66 years. 
 Females: not stated. 
 Major liver resections: not stated. 
 Cirrhotic livers: not stated.
Inclusion criteria: 
 Liver resection.
Interventions Participants were randomly assigned to two groups.
Group 1: low CVP (n = 20). 
 Group 2: control (n = 20).
Further details of intervention: 
 CVP was lowered by clamping the infra‐hepatic inferior vena cava.
Other details: 
 Vascular occlusion: intermittent PTC. 
 Method of parenchymal transection: CUSA. 
 Management of raw surface: diathermy, sutures, fibrin glue. 
 Other co‐interventions to decrease blood loss: none reported.
Outcomes The outcomes reported were mortality, transfusion requirements, and hospital stay.
Notes Attempts to contact the authors in November 2008 were unsuccessful.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Eighty‐five patients who underwent hepatic resection....randomly assigned to an IVC clamping or an IVC non‐clamping group by the minimization method with stratified factors of age, .."
Allocation concealment (selection bias) Low risk Quote: "Eighty‐five patients who underwent hepatic resection....randomly assigned to an IVC clamping or an IVC non‐clamping group by the minimization method with stratified factors of age, .."
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Comment: This information was not available.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comment: This information was not available.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: There were no post‐randomisation drop‐outs.
Selective reporting (reporting bias) High risk Comment: Important outcomes such as liver failure were not reported.
Free of vested interest bias? Unclear risk Unclear.