Matot 2002.

Methods	Randomised clinical trial.
Participants	Country: Israel. Number randomised: 78. Post‐randomisation drop‐outs: not stated. Mean age: 56.5 years. Females: 47 (60.3%). Major liver resections: 78 (100%). Cirrhotic livers: not stated Inclusion criteria: > 18 years Elective major liver resection ASA I or II Pre‐operative haematocrit > 36% No cardiovascular or pulmonary disease. Exclusion criteria: Severe liver dysfunction.
Interventions	Participants were randomly assigned to two groups. Group 1: haemodilution (n = 39). Group 2: control (n = 39). Further details of intervention: haemodilution by withdrawing blood and replacing it with colloids to a target hematocrit of 24%. Other details: Vascular occlusion: not stated. Method of parenchymal transection: not stated. Management of raw surface: not stated. Other co‐interventions to decrease blood loss: none reported.
Outcomes	The outcome measures were transfusion requirements, peri‐operative morbidity, operating time, blood loss, and liver function tests.
Notes	Attempts to contact the authors in November 2008 were unsuccessful.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "On admission to the operating room, patients who met inclusion criteria were randomly assigned (random numbers) to one of two groups..."
Allocation concealment (selection bias)	Unclear risk	Comment: This information was not available.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Quote: "The anaesthesiologist making decisions regarding transfusion was not blinded to patient group assignment."
Blinding of outcome assessment (detection bias) All outcomes	High risk	Quote: "The anaesthesiologist making decisions regarding transfusion was not blinded to patient group assignment."
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Comment: This information was not available.
Selective reporting (reporting bias)	High risk	Comment: Important outcomes such as liver failure were not reported.
Free of vested interest bias?	Unclear risk	Comment: This information was not available.