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. 2019 Aug 27;10(50):5126–5135. doi: 10.18632/oncotarget.27025

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Copyright: © 2019 Kovalski et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A–C) Ras isoform specific proximal proteome networks with selected interactors. Connections between non-Ras nodes are defined as known interactors having experimental/biochemical data of the interaction, interaction between putative homologues, or association in STRING curated databases. Proximal Ras interactors colored by Gene Ontology (GO) terms. (D) Enriched biological process GO terms for each of the 3 Ras isoform specific proximal interactomes. (E) Enriched molecular function GO terms for the 3 Ras isoform unique proximal proteomes. Size of circles (Gene Ratio) indicates the fraction of proteins within the interactome specific to that GO term. Benjamini-Hochberg adjusted p-value.