Figure 5.

Comparison of immune cell frequencies in type 1 diabetes (T1D) patients (a–i) and controls (j–r) aged under 11 years and aged 11 years and older. Younger T1D patients (<11 years) differed significantly in older (≥11 years) T1D patients in (a–c) B cell compartment; (d) slan^– CD16^– myeloid dendritic cells (mDC); (e) CD14⁺CD16⁺ non‐classical monocytes; (f–i) T cell subsets. Younger controls (<11 years) differed significantly compared to older (≥11 years) controls in (j–n) B cell compartment and (o–r) T cell compartment. Horizontal lines indicate median values of cell frequencies, and each data point represents an individual subject. P‐values ≤ 0.05 were considered statistically significant in the Mann–Whitney U‐test.