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. 2019 Sep 2;2019(9):CD011462. doi: 10.1002/14651858.CD011462.pub2

Felix 2012.

Methods Parallel RCT
Setting: Mexico
Dates: January 2008–June 2011
Follow‐up: median 17 months (range 6–42 months)
Randomization ratio: 1: 1
CCT: design not specified
Participants 202 men
Inclusion criteria
  • Intermediate‐ or high‐risk men


Exclusion criteria: no details provided
Diagnostic criteria: prostate cancer
Interventions Number of study centers: 1
Run‐in period: not stated
Extension period: not stated
Complex interventions
Hypofractionation arm: 65.75 Gy in 25 fractions
Conventional arm: 73.8 Gy in 41 fractions
Outcomes Primary outcomes
  • Acute GI and GU toxicity

  • Late GI and GU toxicity


Secondary outcomes: not stated
Complete outcome measures reported: yes
Notes