Table 3.

Mean Standardized Familial Risk Scores for Drug Abuse (DA), Alcohol Use Disorder (AUD) and Non-Affective Psychosis (NAP) in Cases of Schizophrenia, Drug Abuse and Alcohol Use Disorder With and Without a Prior Diagnosis of Substance-Induced Psychotic Disorder (SIPD)

	Genetic Risk Score (NAP)	Genetic Risk Score (DA)	Genetic Risk Score (AUD)
DA – No SIPD	0.13 (0.13; 0.14)	0.82 (0.81; 0.83)	0.56 (0.55; 0.56)
DA – SIPD	0.39 (0.35; 0.44)	1.06 (1.01; 1.12)	0.94 (0.90; 0.98)
P-value difference	<0.0001	<0.0001	<0.0001
AUD – No SIPD	0.09 (0.08; 0.09)	0.25 (0.24; 0.25)	0.53 (0.53; 0.54)
AUD – SIPD	0.31 (0.27; 0.36)	0.70 (0.65; 0.74)	0.93 (0.89; 0.98)
P-value difference	<0.0001	<0.0001	<0.0001
SZ – No SIPD	0.77 (0.73; 0.82)	0.04 (0.03; 0.06)	0.20 (0.19; 0.22)
SZ – SIPD	0.66 (0.51; 0.80)	0.78 (0.66; 0.91)	0.88 (0.76; 1.00)
P-value difference	0.1676	<0.0001	<0.0001

The p-values (One-sided test) are calculated using a non-parametric approach; the Van der Waerden Scores.