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The effects of 2 and 8 on the intracellular accumulation of [3H]-MX in NCI-H460 and NCI-H460/MX20 cells. The error bars represent the SD value. Ko143 (5.0 μM) was used as positive control for ABCG2-overexpressing cells. ****, P < 0.0001 versus no indole derivatives group, two-way ANOVA.
