Skip to main content
. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Eur J Med Chem. 2019 Jun 24;179:849–862. doi: 10.1016/j.ejmech.2019.06.066

Table 1.

The structure and the selected concentration of monobenzoyl indoles and benzoyl naphthalene

graphic file with name nihms-1534679-t0002.jpg
Compd. R1 R2 *Selected concentration (μM)
1 4-OMe 4-OMe 10
3 4-OMe 2,4-OMe 25
5 4-OMe 3,4,5-OMe 1
6 5-OMe 2-OMe 1
7 5-OMe 3-OMe 10
8 5-OMe 4-OMe 10
9 5-OMe 2,4-OMe 25
10 5-OMe 3,4,5-OMe 1
11 5-OMe 2, 6-OMe 1
12 7-OMe 2, 4-OMe 10
13 4-OH 4-OH 25
15 4-OH 2,4-OH 25
16 4-OH 3,4,5-OH 25
17 5-OH 2-OH 25
18 5-OH 3-OH 25
19 5-OH 4-OH 25
20 5-OH 2,4-OH 25
21 5-OH 3,4,5-OH 25
22 5-OH 2,6-OH 10
23 7-OH 2,4-OH 10
24 / / 10
*

The concentrations that did not decrease the viability of NCI-H460 and NCI-H460/MX20 cells by more than 20%.