Fig. 8.
Representative microphotographs and quantification data showing effects of locking down GHSR-1α on oxidative stress, neuronal degeneration and apoptosis in rh-Ghrelin treated animals at 48h post HI. The MitoSOX-positive cells (A), FJC-positive neurons (B) and TUNEL-positive cells (C) were significantly increased in si-GHSR-1α group when compared with scramble siRNA control group. Top panel indicates the location of staining (small black box). &P < 0.05 vs. HI+ rh-Ghrelin+ Vehicle. Data are represented as mean ± SD, n= 3 for each group. Scale bar = 100μm.