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. Author manuscript; available in PMC: 2019 Sep 17.
Published in final edited form as: Diabetes Metab Res Rev. 2019 May 6;35(6):e3167. doi: 10.1002/dmrr.3167

Figure 2.

Figure 2

statistical parametric mapping approach showing the topographical distribution of the effects of image type, exenatide and obesity on percent signal change (B-D) and the raw fMRI signal at rest (E-F) over the cortical surface. (A) flattened view of cortical template used to align all subjects and hemispheres, with anatomical markers and colored areas representing the regions of interest used for Figure 3–4. (B) map of responses to visual stimulation, averaged across all conditions; (C) map of modulation of visual responses to food vs. non-food stimuli; (D) map of modulation of visual responses during exenatide vs. saline infusion; (E) map of modulation of the raw fMRI signal at rest with exenatide; (F) map of significant modulation of the raw fMRI signal at rest in obese vs. lean participants. B-F maps are thresholded at two-tailed p<0.001 uncorrected.