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. 2019 Sep 2;10:3955. doi: 10.1038/s41467-019-11617-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Model-predicted impact of releases of pgSIT eggs on Aedes aegypti mosquito population density with comparison to releases of Wolbachia-based incompatible insect technique (IIT), release of insects carrying a dominant lethal gene (RIDL), and female-specific RIDL (fsRIDL). Releases are carried out weekly over a 6-month period with release ratios (relative to wild adults) shown in the key. Model predictions were computed using 2000 realizations of the stochastic implementation of the MGDrivE simulation framework⁵ for a randomly mixing Ae. aegypti population of 10,000 adult females and model parameters described in Supplemental Table 10 of Kandul et al. ¹ Previous results suggested that pgSIT releases outcompete those of other suppression technologies when pgSIT mating competitiveness is estimated from lab experiments for Drosophila melanogaster (purple). However, pgSIT and fsRIDL perform similarly well when mating competitiveness is estimated from field releases of RIDL strains of Aedes aegypti (green and red, respectively)