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. 2019 Sep 2;10:3927. doi: 10.1038/s41467-019-11881-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Discovery stage results at the 2q13 locus. Regional association plots for a gestational duration and b postterm birth. SNP position is shown on the x-axis and association (−log10 P value) with gestational duration and postterm birth, respectively, on the left y-axis. The lead SNP, rs7594852, from the gestational duration analysis is represented by a purple diamond, and the other SNPs are colored to reflect their LD with the lead SNP (based on pairwise r² values from the Danish National Birth Cohort). In the postterm birth analysis, rs7607470 had a slightly lower P value, but this SNP is highly correlated with rs7594852 (r² > 0.99), and the latter SNP was selected for the replication stage analyses of both gestational duration and postterm birth. Estimated recombination rates are from HapMap (right y-axis)