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. 2019 Sep 2;8(9):48. doi: 10.1038/s41389-019-0156-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — PPB H&E tissue staining demonstrated vast areas of necrosis following treatment (top panel); Immunohistochemical staining of cleaved caspase-3 demonstrating increased staining in treated tumor samples (black arrows indicate high caspase-3 expressing cells), (middle panel); FGF5 and FGF7 IHC staining showed downregulation of these key FGF pathway molecules in anti-NCAM treated tumor samples (bottom 2 panels); Scale bar; 200 μm