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. 2019 Sep 2;9:12658. doi: 10.1038/s41598-019-49038-8

Figure 1.

Figure 1

A20 deficiency in hematopoietic cells leads to myeloproliferation. (A,B) FACS plots (A) and frequencies (B) of myeloid cells from the peripheral blood (PB) of 14 days old A20Hem-KO and control mice (n = 3). (C,D) FACS plots (C) and frequencies (D) of myeloid cells from the bone marrow (BM) of 14 days old A20Hem-KO and control mice (n = 5). (E–G) FACS plots (E), frequencies (F) and absolute numbers (G) of myeloid cells from the spleen (Sp) of 14 days old A20Hem-KO and control mice (n = 5). (H–J) FACS plots (H), frequencies (I) and absolute numbers (J) of myeloid cells from the liver (Liv) of 14 days old A20Hem-KO and control mice (n = 5). All data represent mean ± SEM. Two-tailed student’s t tests were used to assess statistical significance (*P < 0.05, **P < 0.01, ***P < 0.001).