TABLE 1.
Frequencies of different apoE genotypes with summary descriptive data in the YFS cohort in the 2007 follow-up
| All | ε2/2 | ε3/2 | ε3/3 | ε4/2 | ε4/3 | ε4/4 | |
| Subjects | 2,160 | 4 (0.2) | 142 (6.6) | 1,241 (57.5) | 41 (1.9) | 651 (30.1) | 81 (3.8) |
| Males | 974 (45.1) | 2 (0.2) | 56 (5.7) | 568 (58.3) | 17 (1.7) | 296 (30.4) | 35 (3.6) |
| Females | 1,186 (54.9) | 2 (0.2) | 86 (7.3) | 673 (56.7) | 24 (2.0) | 355 (29.9) | 46 (3.9) |
| Age (years) | 37.6 (5.0) | 36.0 (7.4) | 36.9 (5.1) | 37.7 (5.0) | 38.6 (4.0) | 37.5 (5.1) | 38.0 (4.8) |
| BMI (kg/m2) | 26.0 (4.8) | 36.8 (17.2) | 25.5 (4.8) | 26.0 (4.6) | 25.9 (4.5) | 26.0 (4.8) | 26.3 (5.3) |
| Daily smokers | 398 (18.4) | 1 (25) | 21 (14.8) | 229 (18.5) | 6 (14.6) | 127 (19.5) | 14 (17.3) |
| Daily alcohol consumption (g ethanol) | 11.3 (17.0) | 4.7 (6.5) | 12.4 (18.2) | 11.9 (18.8) | 9.8 (13.9) | 10.0 (13.1) | 11.5 (13.7) |
| Cholesterol-lowering medication | 45 (2.1) | 0 (0.0) | 2 (1.4) | 23 (1.9) | 2 (4.9) | 15 (2.3) | 3 (3.7) |
| Diabetes mellitus type 2 | 22 (1.0) | 0 (0.0) | 2 (1.4) | 15 (1.2) | 0 (0.0) | 5 (0.8) | 0 (0.0) |
| Hypertension | 123 (5.7) | 2 (50.0) | 4 (2.8) | 67 (5.4) | 1 (2.4) | 45 (6.9) | 4 (4.9) |
| Total cholesterol (mmol/l) | 5.05 (0.90) | 4.12 (0.76) | 4.49 (0.82) | 5.03 (0.89) | 4.68 (0.82) | 5.22 (0.89) | 5.28 (0.84) |
| LDL-C (mmol/l) | 3.15 (0.81) | 1.94 (0.30) | 2.48 (0.65) | 3.12 (0.79) | 2.76 (0.68) | 3.36 (0.80) | 3.30 (0.76) |
| HDL-C (mmol/l) | 1.34 (0.33) | 1.17 (0.17) | 1.41 (0.37) | 1.35 (0.33) | 1.35 (0.37) | 1.31 (0.31) | 1.35 (0.41) |
| Triglycerides (mmol/l) | 1.40 (0.93) | 2.22 (0.87) | 1.45 (1.00) | 1.38 (0.93) | 1.36 (0.97) | 1.39 (0.82) | 1.70 (1.43) |
| apoB (g/l) | 1.02 (0.26) | 0.79 (0.16) | 0.87 (0.26) | 1.01 (0.26) | 0.91 (0.23) | 1.07 (0.26) | 1.09 (0.25) |
| apoA-I (g/L) | 1.60 (0.26) | 1.60 (0.22) | 1.66 (0.30) | 1.61 (0.26) | 1.59 (0.25) | 1.57 (0.24) | 1.60 (0.28) |
Values are means (SDs) or n (%). The P values across apoE genotypes are given in supplemental Table S1.