Table 1.

Binding energies and interactions observed between the top pose of each ligand with acetylcholinesterase (AChE) receptor.

Ligand	Binding affinity (kcal/mol)	Interaction(s) with AChE sites
		CAS	PAS
Curcumin	−9.6	√	√
Piperine	−10.5	√	√
Bacoside A	−3.2		√
Chebulinic acid	−6.7		√