Figure 4.
Increased proinflammatory cytokine secretion in B. pertussis-stimulated mo-MΦ/NK co-culture. Mo-MΦ and NK cell single cultures and mo-MΦ/NK co-cultures were stimulated with B. pertussis (B4393, MOI = 10, dashed bars) or left untreated (clear bars) for 22 h. Secreted levels of (A) IL-1β, (B) IL-18, (C) GM-CSF, (D) IL-23, (E) TNFα, and (F) IL-10 were measured in the supernatant (n = 7). Results are expressed as medians with interquartile range. Black dots represent values of individual donors. *p < 0.05.