Fig. 3.

The blood glucose control model. a Model diagram. The letters in the circle indicate the variables of the model, the arrows indicate the flow of molecules, the red lines indicate activation, and the blue line indicates inhibition (see Methods). The best fitting models for subjects #1 and #3 lack the GLP1 components. b Temporal patterns of hormones. The blue lines indicate the temporal patterns of simulations, and the red circles indicate the time course data of experiments. The dose and ingestion pattern are indicated at the top