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. 2019 Aug 27;10:2022. doi: 10.3389/fimmu.2019.02022

Table 3.

Marketed PD-L1 antibodies.

Name (Trade name) Company First FDA approval Medical uses ORR tr-AE (Grade ≥3) (%)
PD-L1+ (%) PD-L1– (%)
Atezolizumab (Tecentriq) Roche Genetech 2016 Urothelial carcinoma, NSCLC 26 9.5 17
Avelumab (Bavencio) Merck Serono and Pfizer 2017 Merkel-cell carcinoma 53.8 4.2 6.8
Durvalumab (Imfinzi) AstraZeneca 2017 Urothelial carcinoma 31 0 4.9

ORR, objective responsive rate to solid tumor; AE, adverse event; tr-AE, treatment-related adverse event; NSCLC, non-small cell lung cancer.

Data source: highlights of prescribing information for Tecentriq, Bavencio, and Imfinzi. ORR and AE data refer to Apolo et al. (36), Massard et al. (37), McDermott et al. (38), Ning et al. (39).