Table 1.
The characteristic of the included studies
| Author | Year of publication | Number of subjects | Age | Study period | The definition of HPV POSITIVITY | The specimen type | HPV assay method | Region classification | Province | City | The quality score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Jin, LM | 2018 | 116441 | 21‐78 | 2013‐2016 | HPV DNA | Exfoliated cells | Sequencing PCR | city | Shanghai | 9 | |
| Zhang, C | 2018 | 33562 | 11‐96 | 2016.1‐2016.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Shanghai | 9 | |
| Wang, X | 2018 | 5655 | 17‐68 | 2014.4‐2015.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Inner Mongolia | 9 | |
| Dong, L | 2017 | 1997 | 35‐45 | 1999.6 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shanxi | Xianghua | 9 |
| Zhou, X. H | 2017 | 2452 | 20‐80 | 2013.3‐2013.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Shanghai | 9 | |
| Xu, H. H | 2017 | 37967 | 15‐90 | 2012.12‐2016.2 | HPV DNA | Exfoliated cells | Real‐time PCR | city | Zhejiang | Taizhou | 8 |
| Zhong, TY | 2017 | 714235 | 16‐77 | 2010.8‐2015.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Jiangxi | Nanchang, Jiu‐jiang, Yingtan, Jingdezhen, Shangrao, Yichun, Xinyu, Pingxiang,Fuzhou, Ji'an, and Ganzhou | 9 |
| Wu, X | 2017 | 2300 | 18‐45 | 2013.3‐2013.7 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangxi | Liuzhou | 9 |
| Abulizi, G. | 2017 | 6000 | 21‐60 | HPV DNA | Exfoliated cells | Real‐time PCR | rural | Xinjiang | Uyghur | 9 | |
| Zhang, J | 2017 | 58650 | 13‐81 | 2012.6‐2016.5 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Sichuan | Chengdu | 8 |
| Qi, ZW | 2017 | 4250 | 18‐69 | 2013.1‐2016.1 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Hebei | Chengde | 8 |
| Shen, XP | 2017 | 20000 | 35‐64 | 2015 | HPV DNA | Exfoliated cells | Real‐time PCR | rural | Ningxia | 7 | |
| Zhang Xiaohong | 2017 | 38408 | Not reported | 2012.3‐2015.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Shaanxi | 7 | |
| Yang, DM | 2017 | 9001 | 22‐84 | 2016.1‐2016.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Hunan | Changsha | 8 |
| Jin, DC | 2017 | 50502 | 18‐50 | 2015.1‐2015.12 | HPV DNA | Exfoliated cells | Real‐time PCR | city | Henan | Zhengzhou | 8 |
| Baloch, Z | 2016 | 17898 | 18‐93 | 2013.10‐2015.2 | HPV DNA | Exfoliated cells | Sequencing PCR | city and rural | Yunnan | 9 | |
| Gu, Y | 2016 | 10501 | 39‐55 | 2014.1‐2015.5 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Shanghai | 9 | |
| Liu, F | 2016 | 2187 | 25‐65 | 2007‐2009 | HPV DNA | Exfoliated cells | Sequencing PCR | rural | Henan | anyang | 9 |
| Wei, F | 2016 | 2378 | 18‐55 | 2014.5‐2014.7 | HPV DNA | Exfoliated cells | Real‐time PCR | city | Guangxi | Liuzhou | 8 |
| Zeng, XX | 2016 | 8284 | 18‐65 | 2012.1‐2012.12 | HPV DNA | Exfoliated cells | Sequencing PCR | city | Guangdong | Heyuan | 9 |
| Niyazi, M | 2016 | 883 | 15‐54 | 2006.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Xinjiang | Hetian | 8 |
| Zhang, Y | 2016 | 3000 | 30‐59 | 2015.3‐2015.6 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Shenzhen | 8 |
| Que, M | 2016 | 21078 | 35‐64 | 2014 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Anhui | 8 | |
| Ji,HY | 2016 | 5892 | 18‐80 | 2013.10‐2015.10 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Qinghai | 9 | |
| Long, Xin | 2016 | 29580 | 16‐81 | 2010.11‐2015.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Chongqing | 9 | |
| Wang, JX | 2015 | 191829 | 35‐65 | 2013 | HPV DNA | Exfoliated cells | PCR & (mass‐spectrometric detection) MSD | city | Jiangsu | Wuxi | 8 |
| Mijit, F | 2015 | 4500 | 20‐69 | 2008.6‐2008.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Xinjiang | Hetian | 8 |
| Zhao, Y | 2015 | 6273 | 17‐59 | 2004.5‐2007.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | — | Beijing, Shanghai, Shenzhen, Shenyang, Shanxi, Henan, Xinjiang | 10 |
| Chen, X | 2015 | 2000 | 21‐65 | 2013.4‐2013.10 | HPV DNA | Exfoliated cells | Sequencing PCR | city | Tianjin | 8 | |
| Hong, H | 2015 | 1373 | 22‐64 | 2012.4‐2012.6 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Zhejiang | Ningbo | 8 |
| Yang, L | 2015 | 9,460 | Not reported | Not reported | HPV DNA | Exfoliated cells | Not reported | city | Shandong | Weihai | 8 |
| Zhao, Q | 2015 | 24817 | 18‐80 | 2012.7‐2013.7 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Hunan | 9 | |
| Li, XL | 2015 | 1008 | 23‐78 | 2014.8‐2014.10 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Hubei | Yichang | 9 |
| Chen, MH | 2014 | 11231 | 25‐74 | 2012.1‐2012.12 | HPV DNA | Exfoliated cells | Sequencing PCR | city | Jiangsu | Wuxi | 8 |
| Jing, L | 2014 | 78355 | 18‐75 | 2011.5‐2012.11 | HPV DNA | Exfoliated cells | Real‐time PCR | city | Guangdong | 9 | |
| Zhu, MH | 2014 | 7796 | 18‐70 | 2012.3‐2012.7 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Huizhou | 8 |
| Pei, YY | 2014 | 1944 | 20‐67 | Before 2014 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Shenzhen | 7 |
| Yang, L | 2013 | 1759 | 24‐77 | 2010.6‐2010.10 | HPV DNA | Exfoliated cells | Real‐time PCR | city | Heilongjiang | Daqing | 8 |
| Wu, EQ | 2013 | 4,215 | 17‐54 | 2006.5‐2007.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | — | Beijing, Shanghai, Shanxi, Henan, and Xinjiang | 10 |
| Zhang, R | 2013 | 10000 | 17‐89 | 2011.3‐2011.5 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shanghai | Fengxian | 9 |
| Wu, XQ | 2013 | 4228 | 19‐59 | 2011.11‐2012.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Guangzhou | 8 |
| Weng, ZC | 2013 | 1029 | Not reported | 2010.10‐2012.5 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Hainan | Haikou | 7 |
| Wu, D | 2013 | 2050 | 15‐91 | 2010.1‐2012.11 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Beijing | 8 | |
| Wang, S | 2012 | 24041 | 18‐60 | 2007‐2010 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Liaoning | 9 | |
| Wang, Y | 2012 | 3052 | 20‐79 | 2011.3‐2012.3 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Fujian | 8 | |
| ZhangJing | 2012 | 3685 | 29‐67 | 2010.7‐2011.6 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shaanxi | 8 | |
| Chen, JC | 2012 | 3399 | 26‐59 | 2010.1‐2011.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Shantou | 8 |
| Wang, YY | 2012 | 9683 | Not reported | 2006.4‐2010.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Shenzhen | 7 |
| Zhao, R | 2011 | 5552 | 25‐54 | 2006.9‐2008.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Beijing | 9 | |
| Liu, SS | 2011 | 1570 | Not reported | 2007.1‐2008.4 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Hong Kong | 9 | |
| Ablimit, T | 2011 | 400 | 26‐65 | 2008.7‐2008.9 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Xinjiang | Hetian | 7 |
| Liu, JX | 2011 | 4874 | 24‐55 | 2008.7‐2010.12 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Guangxi | 8 | |
| Chen HC | 2011 | 10602 | 30‐65 | 1991‐1992 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Taiwan | 9 | |
| Yip, Y. C | 2010 | 1600 | 20‐60 | 2008.5‐2008.8 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Macao | 8 | |
| Ye, J | 2010 | 4987 | 20‐79 | 2007.11‐2008.8 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Zhejiang | 9 | |
| Wu, D | 2010 | 2338 | 20‐70 | 2008.5‐2009.5 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Fujian | Fuzhou | 9 |
| Jiang, Y | 2010 | 4911 | 20‐69 | 2008.4‐2008.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Fujian | Xiamen | 8 |
| Zhouyuan | 2010 | 20905 | 14‐84 | 2008.10‐2009.3 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Zhejiang | 9 | |
| Jin, Q | 2009 | 3036 | 19‐65 | 2007.8 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Xizang | Lhasa, Shigatse, Nagqu | 9 |
| Li, N | 2008 | 2374 | 15‐59 | 2004.5‐2006.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city and rural | Shanxi, Guangdong, Liaoning | 10 | |
| Chao A | 2008 | 10014 | 30‐ | 2004.6‐2005.6 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Taiwan | 9 | |
| Zhang, X | 2007 | 702 | 19‐59 | 2006.8‐2006.9 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Liaoning | Shenyang | 9 |
| Dai, M | 2006 | 662 | 15‐59 | 2004.3‐2004.4 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shanxi | 9 | |
| Li, LK | 2006 | 685 | 15‐59 | 2005.6‐2005.7 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Liaoning | Shenyang | 9 |
| Shi, JF | 2006 | 1137 | 15‐59 | Before 2006 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Shenzhen | 9 |
| Wu, KH | 2004 | 500 | 21‐45 | 1999.7‐2001.6 | HPV DNA | Exfoliated cells | PCR & hybridization | city | Guangdong | Guangzhou | 8 |
| Chen Feng | 2004 | 3233 | 30‐50 | 2002 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shanxi | 8 | |
| Shen Yanhong | 2003 | 9683 | 30‐50 | Before 2003 | HPV DNA | Exfoliated cells | PCR & hybridization | rural | Shanxi | 8 |
Because the number of references was too much, the authors made the references of the included studies in Supplementary Data S2.