Table 2.
The pooled prevalence of Human papillomavirus (HPV) infection in Chinese women
| Number of databases | Number of Subjects | Prevalence (%) | 95% CI | |
|---|---|---|---|---|
| Overall | 71 | 1705956 | 15.54 | 13.83‐17.24 |
| Subgroup Analysis | ||||
| Areas | ||||
| Urban | 50 | 1488733 | 14.86 | 12.84‐16.88 |
| Rural | 21 | 113946 | 13.70 | 11.18‐16.22 |
| East China | 18 | 1197096 | 15.99 | 12.84‐19.13 |
| North China | 13 | 35761 | 18.43 | 13.39‐23.46 |
| Central China | 5 | 79393 | 12.96 | 8.44‐17.48 |
| South China | 20 | 155199 | 13.51 | 11.34‐15.68 |
| Southwest | 4 | 109164 | 12.92 | 5.31‐20.53 |
| Northwest | 9 | 80651 | 12.57 | 8.49‐16.65 |
| Northeast | 6 | 33552 | 19.85 | 3.46‐36.23 |
| GDP | ||||
| High | 36 | 631416 | 13.41 | 11.74‐15.09 |
| Middle | 15 | 178795 | 18.01 | 12.67‐23.35 |
| Low | 22 | 859989 | 13.48 | 11.57‐15.39 |
| HPV Assay Method | ||||
| PCR & hybridization | 57 | 1167563 | 16.55 | 14.53‐18.56 |
| Sequencing or real‐time PCR | 12 | 337104 | 11.73 | 9.34‐14.11 |
| HPV types | ||||
| High risk HPV | 66 | 1426787 | 11.93 | 10.93‐12.92 |
| Low risk HPV | 46 | 1176995 | 2.78 | 2.35‐3.20 |
| HPV infection types | ||||
| Single infection | 35 | 1424052 | 11.00 | 9.32‐12.68 |
| Multiple infection | 48 | 1419715 | 3.44 | 2.69‐4.18 |
| Dual infection | 14 | 445316 | 2.30 | 2.01‐2.58 |
| Triple infection | 13 | 442280 | 0.51 | 0.42‐0.60 |
| Fourfold infection | 9 | 406238 | 0.11 | 0.07‐0.15 |
| Fivefold infection | 5 | 204499 | 0.04 | 0.01‐0.07 |
| The top 10 subtypes | ||||
| HPV 16 | 68 | 1604203 | 3.52 | 3.18‐3.86 |
| HPV52 | 65 | 1574238 | 2.20 | 1.93‐2.46 |
| HPV58 | 65 | 1579921 | 2.10 | 1.88‐2.32 |
| HPV18 | 60 | 1566134 | 1.20 | 1.05‐1.35 |
| HPV33 | 54 | 1524449 | 1.02 | 0.89‐1.14 |
| HPV31 | 52 | 1467424 | 0.84 | 0.74‐0.95 |
| HPV51 | 50 | 1487714 | 0.72 | 0.64‐0.81 |
| HPV 56 | 49 | 1415424 | 0.66 | 0.57‐0.74 |
| HPV6 | 48 | 1500726 | 0.63 | 0.48‐0.78 |
| HPV11 | 45 | 1506233 | 0.56 | 0.43‐0.69 |