Table 1. Clinical Trials on evening primrose oil (EPO) in management of premenstrual syndrome (PMS).
| Trial/ailments | Intervention/d | Results |
|---|---|---|
| Meta-analysis on 7 placebo-controlled trial, PMS [10] | 3-6 g EPO | Safety of EPO |
| No scientific results due to small sample size | ||
| Randomized double-blind placebo controlled parallel design, PMS [11] | 180 mg GLA, placebo | Increase in GLA, DGLA in plasma phospholipid |
| Improvement of PMS severity and duration | ||
| Placebo randomized control trial, PMS [12] | 1.5 g EPO, placebo | Significant reduction in PMS severity score |
GLA: γ-linolenic acid, DGLA: dihomo-γ-linolenic acid.