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KDM1A (LSD1) inhibitors and GFI1. GFI1 interacts with the histone demethylase LSD1 through its SNAG domain. New data suggest that small molecule inhibitors lead to an eviction of both LSD1 and GFI1 from the DNA (77, 79) and a dissociation of at least part of the HDAC molecules associated with GFI1.
