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. 2019 Aug 27;10:1002. doi: 10.3389/fphys.2019.01002

TABLE 5B.

The PROBAST Tool for severity.

Study Risk of bias Applicability concerns Overall
Partici-pants Predictors Outcome severity Ana-lysis Partici-pants Predictors Outcome severity Risk of bias Appli-cability
CTSI BISAP MCTSI CRP Ran-son Apache II CTSI BISAP MCTSI CRP Ran-son Apache II
Cho et al., 2015 N/A N/A
Gurleyik et al., 2005 N/A N/A N/A + N/A N/A N/A +
Lee et al., 2016 N/A ? + N/A ? +
Qiu et al., 2015 N/A N/A N/A N/A N/A N/A
Yue et al., 2015 + N/A N/A N/A + N/A N/A N/A + +
Bollen et al., 2011 N/A N/A N/A ? + N/A + N/A N/A ? +
Yang et al., 2016 N/A N/A ? + N/A N/A +
Bollen et al., 2012 N/A N/A + N/A N/A +
Alper et al., 2016 N/A N/A N/A N/A N/A + + N/A N/A N/A N/A N/A + +
Zhao et al., 2016 N/A N/A N/A + N/A N/A N/A +
Fabre et al., 2012 + N/A N/A N/A N/A ? + N/A N/A N/A N/A ? N/A + +
Hashimoto et al., 2016 ? N/A N/A N/A ? N/A N/A + + ? N/A N/A N/A ? N/A ? + +
Park et al., 2013 N/A + N/A +
Khanna et al., 2013 + N/A + N/A N/A +
Lautz et al., 2012 + N/A N/A N/A ? N/A ? + + N/A N/A N/A ? N/A N/A + +
Chatzicostas et al., 2003 N/A N/A N/A ? N/A N/A N/A
Xu et al., 2014 + N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A +
Yadav et al., 2016 + N/A N/A N/A + N/A N/A N/A + +
Papachristou et al., 2010 + N/A N/A + N/A N/A + +
Huang et al., 2010 N/A N/A N/A N/A N/A + N/A N/A N/A N/A N/A +
Fei et al., 2018 ? N/A N/A + N/A N/A ? +
Kumar et al., 2017 ? N/A N/A N/A ? N/A N/A N/A ?

red, high risk of bias or concern; yellow, unclear risk of bias or concern; green, low risk of bias or concern; +, high risk of bias or concern; ?, unclear risk of bias or concern; −, low risk of bias or concern.