Figure 6.

GLUT4 expression in the membrane fractions of the hippocampi of hIAPP^−/− and hIAPP^+/– mice was reduced by a high-fat diet. (A) Representative images of Western blot analysis. (B) Quantitative analysis was performed on the basis of gray density by using ImageJ software. L^−/− denotes hIAPP^−/− mice on a low-fat diet; L^+/– denotes hIAPP^+/– mice on a low-fat diet; H^−/− denotes hIAPP^−/− mice on a high-fat diet; H^+/– denotes hIAPP^+/– mice on a high-fat diet. n = 6, *p < 0.05, **p < 0.01, ***p < 0.001 compared with the L^−/− group.