BST2 Paralogs and Phylogeny
We identified four BST2 paralogous genes in the genome of M. lucifugus that served as a reference in this study. From the de novo transcriptome assembly of the M. daubentonii RNA-seq data, we were able to distinguish only three different BST2-like mRNAs.
(A) The box plots show arithmetic means and standard deviations from the DESeq2-normalized expression values of the M. daubentonii RNA-seq reads, uniquely mapped to the M. lucifugus reference genome.
(B) Phylogenetic tree of twelve selected mammalian BST2 genes and the four and three BST2 paralogs identified in the M. lucifugus genome or M. daubentonii transcriptome, respectively.