Table 2.

Outcome variables by IV APAP use.

Study outcomes	IV APAP Use				Pb
	Yes (n = 11,949)		No (n = 55,545)
	n	%	n	%
Resource utilization
Oral morphine equivalentsa	226	111–295	233	113–310	<0.0001
Length of hospital staya	2	1–2	2	1–2	<0.0001
Cost of hospitalizationa	$18,425	$13,495–$21,514	$17,938	$13,146–$21,058	<0.0001
Opioid-related adverse effects
Respiratory	197	1.6	1075	1.9	0.0366
Gastrointestinal	165	1.4	720	1.3	0.4607
Central nervous system	72	0.6	348	0.6	0.7626
Genitourinary system	347	2.9	1187	2.1	<0.0001
Other	70	0.6	427	0.8	0.0339
Use of naloxone	95	0.8	552	1.0	0.0431

IV APAP = intravenous acetaminophen.

^aContinuous variables median and interquartile range reported, instead of N and %, respectively

^bChi-square test for categorical variables, t test for continuous variables.