Table 2.

Phenolic compounds of M. aquatica, L. dentata and L. cardiaca hydroethanolic extracts determined by UHPLC-DAD-ESI-MSⁿ.

-					Plant Extract
					M. aquatica	L. dentata	L. cardiaca
Peak	RT (min)	λmax (nm)	Compound	ESI—MSn Fragmentation (m/z)	Phenolic Content (μg/mg of extract)
	Caffeic acid derivatives
1	8.2	290,329	Caffeic acid glc	341→179→135	-	-	3.7 ± 0.8
16	21.1	290,328	Rosmarinic acid	359→179→135, 161	64.2 ± 8.8	67.8 ± 6.7	-
	Phenylethanoid glycosides
5	16.7	290,329	Lavandulifolioside	755→593→461→315	-	-	253.6 ± 35.8
7	17.5	290,329	Verbascoside	623→461→315→135	-	-	137.4 ± 19.9
14	19.4	ND	Leucoseptoside A	637→461→315→135	-	-	31.5 ± 4.6
15	20.0	ND	Leonoside B	783→607→475→329	-	-	25.1±4.7
	Flavones
6	16.8	254,267,345	Luteolin-7-O-rut	593→285→241	43.3 ± 10.0	-	-
10	18.1	253,267,345	Luteolin-7-O-glcA	461→285→241	D	26.2 ± 4.0	-
12	18.9	ND	Luteolin-7-O-rut	593→285→257	-	-	D
17	21.1	266,329	Apigenin-7-O-gl	431→269→225	-	D	-
18	26.3	266,330	Apigenin-7-O-(6″ acetyl)glc	473→269, 413	-	D	-
	Flavonols
2	8.2	ND	Rutin-O-glc	771→609→301	-	D	-
3	13.7	ND	Quercetin-3-O-soph	625→301→179	-	-	5.7 ± 1.1
9	18.0	256,267,355	Rutin	609→301→179	-	-	15.8 ± 2.1
11	18.9	256,267,357	Quercetin-3-O-glc	463→301→179	-	-	24.9 ± 3.8
	Flavanones
4	15.0	283,325sh	Eriodictyol-O-rut	595→287→151→107	144.6 ± 22.4	-	-
8	17.9	282,333sh	Naringenin-7-O-rut	579→271→151	24.4 ± 3.7	-	-
13	19.5	283,325sh	Hesperetin-7-O-rut	609→301→286→241	25.9 ± 3.6	-	-

D, Detected; Glc, Glucoside; GlcA, Glucuronide; RT, retention time; Rut, Rutinoside; Soph, Sophoroside; Mean values ± standard deviations; Numbers correspond to the UHPLC-DAD-ESI-MSⁿ peaks described in chromatograms in Figure 1. Supplementary Material S1.