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. 2019 Aug 13;20(16):3935. doi: 10.3390/ijms20163935

Figure 3.

Figure 3

(A) Effects of melatonin on docetaxel- and vinorelbine-induced changes on intracytoplasmic triglyceride content in breast fibroblasts during the course of differentiation, in the presence of human breast cancer cells (MCF-7). Data are expressed as the percentage of the differentiated adipocytes (C) (mean ± SEM). a, p < 0.001 vs. C; b, p < 0.05 vs. C; c, p < 0.001 vs. differentiated adipocytes co-cultured with MCF-7 cells; d, p < 0.001 vs. differentiated adipocytes co-cultured with MCF-7 cells and docetaxel (D, 1 µM); e, p < 0.05 vs. differentiated adipocytes co-cultured with MCF-7 cells and D (1 µM) and melatonin (M, 1 mM); f, p < 0.001 vs. differentiated adipocytes co-cultured with MCF-7 cells and vinorelbine (V, 1 µM). (B) Representative images of the Oil Red O staining.