Table 3.
Effect of treatment with TOL and TOR on tissue TAC and MDA levels after 21 days.
| Group/Organ | Heart | Liver | Kidney | Brain | ||||
|---|---|---|---|---|---|---|---|---|
| TAC (mg AAE/mL) | MDA (µM) | TAC (mg AAE/mL) | MDA (µM) | TAC (mg AAE/mL) | MDA (µM) | TAC (mg AAE/mL) | MDA (µM)) | |
| Control Norm. | 84.9 ± 27.1 | 1.2 ± 0.1 | 80.1 ± 2.5 | 1.1 ± 0.1 | 77.7 ± 5.5 | 1.7 ± 0.1 | 31.1 ± 5.8 | 1.7 ± 0.1 |
| Control HTN | 44.9 ± 0.1 | 3.2 ± 0.5 *** | 36.6 ± 24.1 | 3.1 ± 0.2 *** | 75.1 ± 8.8 | 3.1 ± 0.4 | 5.1 ± 1.8 *** | 2.6 ± 0.5 |
| TOL | 59.3 ± 6.2 | 1.9 ± 0.1 # | 104.1 ± 20.9 | 3 ± 0.2 *** | 312.8 ± 38.1 ***### | 6.4 ± 0.8 ### | 15.7 ± 2.2 ***## | 3 ± 0.4 |
| TOR | 43.8 ± 3.5 | 2.9 ± 0.3 ## | 186.8 ± 19.4 *## | 3 ± 0.2 *** | 333.3 ± 14.8 ***### | 4.4 ± 0.3 ** | 13.7 ± 1.4 ***# | 2.1 ± 0.3 |
Control Norm. = Normotensive controls, Control HTN = Hypertensive control; TOL = T. officinale leaf extract-treated animals; TOR = T. officinale root extract-treated animals. AAE = Ascorbic acid equivalent. Data are presented as mean ±SEM. * p < 0.05, ** p < 0.01, *** p < 0.001 compared to normotensive control animals. # p < 0.05, ## p < 0.01, ### p < 0.001 compared to hypertensive control animals.