| Oral semaglutide had no clinically relevant effect on the exposure of lisinopril, warfarin, digoxin, and metformin, which are all commonly used in patients with type 2 diabetes. |
| Oral semaglutide was found to be well tolerated in combination with these drugs and no new safety issues were identified. |
| These findings suggest that lisinopril, warfarin, digoxin, and metformin require no dose adjustment when coadministered with oral semaglutide. |
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