Table 2.

Demographic data and histopathological characteristics for high-grade and low-grade tumours

	Low-grade glioma	High-grade glioma	p
Age in years	33.2 ± 9.2 (24–45)	55.3 ± 11.9 (44–78)	< 0.01
Men, n (%)	2 (28.6)	4 (57.1)	0.59
Lesion size in mm	44.4 ± 19.1 (23.1–68.7)	27.1 ± 17.2 (6.4–56.4)	0.13
IDH1 R132Ha, n (%)
Present	7 (100)	0 (0)	< 0.01
Absent	0 (0)	7 (100)
MIB-1 (a.u.)	4.2 ± 3.0 (1–8.8)	19.2 ± 6.7 (12–31)	< 0.001

The monoclonal antibody MIB-1 was used to determine the Ki-67 labelling index as a marker of proliferation. Continuous values are expressed as mean ± SD with range in parentheses

^aMutations involving isocitrate dehydrogenase 1