Table 2.

Results of Meta-analysis for Defocus Curve

Defocus levels	MD [95% CI]	P value	Heterogeneity
			I2 (%)	P heterogeneity
EDOF vs. Monofocal IOLs
-0.01	−0.00 (− 0.10, 0.08)	0.81	89	0.0001
−0.50	−0.04 (− 0.09, 0.00)	0.07	25	0.26
−1.00	−0.16 (− 0.21, − 0.12)	< 0.00001	0	0.65
− 1.50	− 0.22 (− 0.31, − 0.13)	< 0.00001	63	0.07
−2.00	− 0.24 (− 0.29, − 0.19)	< 0.00001	8	0.34
− 2.50	− 0.22 (− 0.27, − 0.16)	< 0.00001	0	0.45
− 3.00	− 0.25 (− 0.31, − 0.18)	< 0.00001	37	0.20
−3.50	− 0.21 (− 0.26, − 0.16)	< 0.00001	0	0.94
−4.00	−0.21 (− 0.26, − 0.16)	< 0.00001	0	0.73
EDOF vs. Trifocal IOLs
0.00	−0.02 (− 0.07, 0.03)	0.40	59	0.06
−0.50	−0.03 (− 0.08, 0.01)	0.17	52	0.10
−1.00	−0.04 (− 0.10, 0.01)	0.11	55	0.08
−1.50	−0.01 (− 0.08, 0.07)	0.88	76	0.006
−2.00	0.03 (−0.01, 0.07)	0.19	0	0.96
−2.50	0.10 (0.06, 0.15)	< 0.00001	0	0.79
−3.00	0.17 (0.09, 0.26)	< 0.0001	65	0.04
−3.50	0.19 (0.07, 0.30)	0.002	68	0.04
−4.00	0.21 (0.07, 0.35)	0.003	79	0.008

IOL intraocular lens, MD mean difference, CI confidence interval, I² extent of inconsistency